Conrad's ex-fiancé, Catherine, is admitted to the hospital with abdominal pain that proves to be quite the medical mystery. As Conrad doggedly tries to figure out her diagnosis and fights the idea of Bell performing her operation, Nic gets some insight into Conrad's past.

When astrophysicists detect a transmission from another galaxy, it is definitive proof of intelligent extra-terrestrial life. The world's population waits for further contact with baited breath. They do not have to wait long. Within days, mankind is all but wiped out; just pockets of humanity are left in an eerily deserted world.

After the devastating alien attack, disparate pockets of survivors emerge into a shattered world. They quickly realise they must put their differences aside if they are to stand any chance of survival.

Oh no! The Red Goobler's back and this time he's jacked! This one's too scary for me.

Oh no! The Red Goobler's back and this time he's jacked! This one's too scary for me.

Korvo tries to get the family involved in repairing the spaceship, but they attend a birthday party instead, where he is inspired to become a magician. Using his computer system Aisha, Korvo creates a technologically advanced magic act; he goes viral and prepares for a Las Vegas show, which will culminate in him leaping through a black hole. Korvo ignores his family's warning that jealous magicians plan to kill him; the family save him from being shot, but he dies when the black hole trick goes awry. The grieving family agree to repair the ship in Korvo's memory, and he reappears, having faked his death to bring them closer together. Yumyulack adds a woman named Cherie to his shrunken collection.

With Richard's help, Catherine discovers she can travel to another world; a new revelation puts Martha's loyalties to the test; Zoe breaks Bill out of prison.

Tom grapples with a betrayal and encounters a familiar face; Catherine looks for a solution to the dangers of the black hole.

A deadly face-off leads to a life-threatening moment; Catherine and Sam seek help for his parents.

Conrad's ex-fiancé, Catherine, is admitted to the hospital with abdominal pain that proves to be quite the medical mystery. As Conrad doggedly tries to figure out her diagnosis and fights the idea of Bell performing her operation, Nic gets some insight into Conrad's past.

Conrad is hit by a bike and badly sprains his ankle, but works through it when he takes the case of his old medical professor, who is hallucinating visions of her old patients. Devon is tasked with admitting Conrad, who refuses any sort of treatment.

It's Thanksgiving and while Meredith faces travel complications, due to the weather, Nick steps in to help – in more ways than one. Richard and Bailey seek out emergency surgeries; Amelia and Link reconnect.

Dr. Hamilton takes his frustrations out on Meredith, so Nick gives her a chance to blow off steam by scrubbing in on a surgery. Back in Seattle, Link and Jo take their kids to a fairytale theater performance that goes wrong. Bailey and Dr. Lin attend a recruitment fair in hopes of attracting more doctors to Grey Sloan but find themselves ill-prepared.

The doctors celebrate the holidays. Hamilton and Meredith prepare for a milestone on their project, while Link wants to spend the holiday with Amelia and Scout as a family. Schmitt is faced with a difficult decision during surgery.

The Grey Sloan Memorial doctors grapple with the aftermath of the car crash that involved some of their own. Meredith works to save Dr. Hamilton's life; Levi is impacted from his latest loss.

In the wake of national outcry after the tragic murder of an unarmed Black man, Maya brings in Dr. Diane Lewis to grief counsel the team.

Ben and Dean wrestle with life and death after the Black Fighter's Coalition banquet.

Ben finally faces the health issues he has been putting off. Meanwhile, Jack and Inara help their neighbor out of a trashy situation, and Carina and Maya reevaluate their relationship.

"Lynette locks horns with officious mom Maisy Gibbons at the twins' school who is trying to produce a ""politically correct"" play about ""Little Red Riding Hood."" Meanwhile, Susan continues to investigate the mystery of Zach's sudden disappearance. She soon finds out his father Paul put him in Seacrest, a mental institution. She and Julie then go to investigate. Mama Solis comes closer to discovering Gabrielle's dirty little secret of her affair, and Bree comes undone when Rex suggests they hire a sex surrogate."

Susan and Edie decide to follow Mike and his houseguest Kendra on their night out together. Lynette becomes steadily more dependent on the twins' ADD medication. In the meantime Gabrielle becomes jealous of the "other" woman in John's life. And Bree's kids mutiny when they learn their dad has moved out. Tom is not happy when Lynette tries to take over his concept of new "Spotless Scrubs" to his clients.

Although Detectives Morris and Baker are ready to attribute a double murder as a murder-suicide, Megan and the team find evidence to the contrary. Peter suggests that if Megan wants to reunite with her daughter she should go slowly.

Andy, Sullivan, Dean and Ben are faced with a tough choice while trying to save a couple trapped in their car. Travis' dad fears he will be outed when his "golfing friend" is exposed to COVID-19.

Maya, Jack, Vic, Travis and Sullivan respond to a burn call at an ice rink. Meanwhile, a pregnant woman and her husband seek out the station for help; and Maya and Carina have a difficult conversation.

Megan probes more deeply into her father's suicide so much that she finally gets some closure.

Dr. Megan Hunt was in a class of her own, a brilliant neurosurgeon at the top of her game. Her world is turned upside down when a devastating car accident puts an end to her time in the operating room. Megan resumes her career as a medical examiner determined to solve the puzzle of who or what killed the victims.

Although Detectives Morris and Baker are ready to attribute a double murder as a murder-suicide, Megan and the team find evidence to the contrary. Peter suggests that if Megan wants to reunite with her daughter she should go slowly.

A nanny is found bludgeoned to death in the park; Morgan interferes when Elliot admits to not being invited to his classmate's party.

A mysterious death in an empty high-rise pulls Rosie and Villa into the inner circle of a former child star who may be planning a comeback. Meanwhile, Rosie is feeling the effects of Donna’s involvement at Magic City Lab, and shocking revelations from Hornstock and Rosie elevate their relationship to a new level.

Bailey and Blue are forced to confront the emotional costs of experimental care; Owen, Teddy, Simone and Dani help out at a busy rural hospital; Richard attempts to spread information about early prostate screenings to the community.

Schmitt must face the Morbidity and Mortality Conference. Meredith convinces Nick to scrub in on a surgery in Seattle. Jo faces her feelings.

Meredith, Amelia and the team prepare for Dr. Hamilton's long-awaited groundbreaking surgery while Bailey receives an unexpected offer. Owen's impatience makes him a difficult physical therapy patient, forcing Link to intervene.

It's Valentine's Day on Wisteria Lane, and love is all around (sort of), as Susan looks forward to a romantic date with Mike, until she learns a surprising fact about her favorite plumber. Meanwhile, after reconciling their relationship, Bree discovers something new about her husband Rex when it comes to his sexual needs. Lynette's neighbor accuses the Scavo twins of thievery as Lynette tries her best to handle the situation. Lastly, Gabrielle's work adventures continue as she gets a gig as a mattress model.

Richard ponders his surgical abilities. Jo is charmed by her patient's brother; Megan makes sure Teddy and Owen talk out their differences. A pet python causes an uproar.

Tensions at Grey Sloan Memorial rise as the effects of the physician shortage begin to show. Meredith struggles to step away from work as she spends a sick day at home with Zola. The hospital receives an unexpected visitor.

When Nic finds herself under investigation in Lily's death, Conrad comes to her defense, but ends up making the situation worse. During a routine surgery, Bell's patient accidentally catches fire, leaving the hospital to start an immediate investigation into his medical records.